In this chapter, we describe advances in our understanding of GIRK channel function based on recent high-resolution atogirkmic structures of inwardly rectifying K (+) channels discussed in the context of classical structure-function experiments.
G-protein-gated inwardly rectifying K + (GIRK) channels play a key role in maintaining resting membrane potential, cell excitability and inhibitory neurotransmission.
G Protein-Coupled Inwardly-Rectifying Potassium Channels (GIRK channels) are channels found in the brain that play a crucial role in the inhibitory effects of neurotransmitters.
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